NAD+ Infusion Therapy

Renew Energy. Restore Clarity. Revitalize Your Well-Being.

Modern life is demanding — long workdays, chronic stress, disrupted sleep, and the natural aging process can leave you feeling drained, foggy, and worn down. When your energy dips and your mental clarity fades, even everyday tasks can feel overwhelming.

At Crestline Health and Wellness, we offer NAD+ infusion therapy to help replenish your body at a cellular level. Whether you’re looking to boost energy, support cognitive health, recover from burnout, or promote healthy aging, NAD+ offers a restorative, science-backed solution to help you feel like yourself again.

What Is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body that plays a key role in energy production and DNA repair. NAD+ is known to promote brain health by supporting mitochondrial function, reducing inflammation and improving neurotransmitter balance. This can help with depression, anxiety, addiction recovery and cognitive decline.

As we age — and as stress, illness, and lifestyle factors accumulate — NAD+ levels naturally decline, contributing to fatigue, brain fog, inflammation, and slower recovery.

NAD+ infusions deliver this essential coenzyme directly into your bloodstream, allowing your body to absorb and use it immediately for deep, whole-body rejuvenation.

Ketamine and NAD+ Therapy for Mental Health

NAD+ (Nicotinamide Adenine Dinucleotide) and ketamine work synergistically, with ketamine promoting new synaptic connections and NAD+ protecting neurons from oxidative stress. 

This combination improves overall brain function and energy metabolism, enhancing cognitive recovery, particularly for patients with mood disorders or neurodegenerative conditions. 

Additionally, NAD+ reduces inflammation and supports mitochondrial function, which complements ketamine’s neuroplasticity effects, resulting in enhanced mood, focus, and emotional resilience.

Together, these therapies offer a holistic approach to healing, addressing both the biological and psychological aspects of recovery and integration.

Benefits of NAD+ Infusion Therapy

Patients often describe NAD+ therapy as a reset — a way to restore energy, focus, and vitality from the inside out. Here are 5 key benefits of NAD+ Infusion therapy:

  • Reduces Inflammation: Inflammation can cause damage to cellular DNA. NAD+ IV therapy activates enzymes that prevent and correct DNA damage caused by inflammatory foods, inhaled pollutants, and exposure to toxic chemicals.
  • Combats Fatigue and Increases Energy: Levels of NAD+ decline as we age and is associated with decreased motivation and energy. NAD+ IV therapy helps supply your body with the energy and drive it needs on a cellular level.
  • Improved Mental Clarity: As we age, our cognitive abilities may decline. NAD+ IV therapy helps increase concentration and focus, as well as, improve memory and mood. This enables you to be more productive, make better decisions and enjoy a better quality of life.
  • Support during burnout or chronic stress: Oxidative stress, an imbalance between free radicals and your body’s ability to counteract them with antioxidants can deplete your natural NAD+. NAD+ IV therapy restores this vital coenzyme allowing your body to ward off the harmful physiological effects of stress and anxiety.
  • Healthier metabolism and aging: By replenishing your supply of NAD+, this effectively addresses aging at the cellular level and helps restore normal metabolism function. 

Whether your goals are physical, mental, or both, NAD+ helps replenish the fuel your body needs to function at its best.

What to Expect During Treatment

NAD+ infusions are administered in a calm, comfortable setting designed for deep relaxation and renewal.

  • Infusion duration: Infusions typically last 120 minutes and are administered via infusion pump for precise, measured dosing.
  • Comfort-focused experience: We’ll adjust your infusion rate to ensure you remain comfortable throughout the treatment.
  • Supervised care: Our team of trained medical professionals monitor you throughout your session.
  • Minimal side effects: Some patients experience temporary sensations such as flushing, headache, chest tightness or mild abdominal discomfort if the infusion runs too quickly — we simply slow it down to keep you comfortable.

After your session, most patients report increased energy, clearer thinking, and a renewed sense of well-being that can last days to weeks.

How Many Treatments Will I Need?

Your ideal treatment plan depends on your goals:

  1. Wellness Boost:
    A single infusion may provide an energizing reset for patients seeking improved clarity and vitality.
  2. Restorative Series:
    Many patients begin with a series of 3–6 infusions spaced over several weeks to deeply replenish NAD+ levels.
  3. Ongoing Maintenance:
    Monthly or seasonal infusions help sustain energy, resilience, and overall wellness long-term.

Dr. Amy will tailor a plan that aligns with your unique health needs and desired outcomes.

Who Can Benefit From NAD+?

NAD+ therapy may be helpful for people experiencing:

  • Chronic fatigue
  • Brain fog or difficulty concentrating
  • Stress or burnout
  • Age-related cognitive changes
  • Metabolic concerns
  • Low energy despite adequate sleep
  • Demanding physical or mental workloads

It can also complement other treatments, such as GLP-1 weight management or ketamine therapy, by supporting whole-body wellness and recovery.

Experience the Difference NAD+ Can Make

If you’re ready to feel clearer, more energized, and more balanced, NAD+ therapy may be the restorative boost your body has been missing.

Contact Crestline Health and Wellness today to schedule your consultation and learn how NAD+ infusion therapy can help you feel revitalized from the inside out.

We’re here to help. MAKE AN APPOINTMENT

COMPASSIONATE CARE

Located in the heart of Mountain Brook, we serve individuals throughout Central Alabama seeking relief from depression, anxiety, chronic pain, weight concerns, burnout, and more. Our clinic blends medical expertise with deeply personalized, patient-first care to help you feel better, function better, and live better.

AFFILIATIONS

May you experience joy, ease and peace.